Quantitative Influenza Antibody (Nasal or Throat Swab) (2024)

Does this test have other names?

Direct immunofluorescence (DFA), indirect immunofluorescence (IFA) antibody staining

What is this test?

This test checks for flu (influenza) antibodies in fluid from your nose or throat.

The fluis a common illness of the respiratory system. It can have serious health effects. It can even cause death, especially if you have a weak immune system.

Influenza A is more common and can be more serious. It spreads easily through fluid droplets in the air. It often affects many people at the same time during the fall and winter months.

Healthcare providers can test for influenza in several ways. One method uses nasal washes and throat swabs to look for influenza antigens. Results are shown quickly, in less than 30 minutes. The test described here uses immunofluorescence. This is a staining method to look for influenza antibodies. Results may be available in 1 to 4 hours. Results from a rapid testing method are not as accurate as a type of influenza test called a viral culture. But a rapid test is often used as a first screening test. A viral culture may take from 3 to10 days to show results.

Why do I need this test?

You may need this test if your healthcare provider thinks that you have the flu. Symptoms of the flu include:

Symptoms of the flu often appear about 1 to 2 days after you are infected.The symptoms may feel severe right away.Your body may fight off an influenza infection within a few days. But some people develop severe pneumonia or other serious problems.

Even if you don't have signs of infection, you should be tested during flu season or an influenza outbreak if you:

  • Were discharged from a hospital and have a sudden fever or respiratory illness

  • Are in the hospital and have a fever or respiratory illness

What other tests might I have along with this test?

Testing for influenza antibodies is a screening test. This means you may need additional tests that are more accurate to confirm your diagnosis. You may have tests such as:

  • Viral culture

  • Rapid antigen test

  • Reverse transcriptase polymerase chain reaction test

What do my test results mean?

Test results may vary depending on your age, gender, health history, and other things. Your test results may be different depending on the lab used. They may not mean you have a problem. Ask your healthcare provider what your test results mean for you.

A negative result meansthat no influenza antibodies were found and you likely don't have the flu.

A positive result means that you do have influenza antibodies. A positive result is more likely to be accurate with this test if other cases of influenza have been reported in your area. It's possible to get a false-positive result. This means that you are not really infected with the flu. Your healthcare provider may do more tests if needed.

How is this test done?

This test is done with a sample of mucus or other fluid from your respiratory system. Your healthcare provider will wipe a sterile swab inside your nose or throat.

Another method of doing this test is done with a nasopharyngeal aspirate (NPA). For this, your healthcare provider will put saline solution in your nose and collect a sample.

Does this test pose any risks?

This test does not pose any serious risks. You may feel discomfort or gag when your throat or nasal cavity is swabbed. An NPA may also cause some discomfort.

What might affect my test results?

Other respiratory infections may cause a false-positive result. Influenza screening tests are sometimes not accurate.

How do I get ready for this test?

You don't need to prepare for this test.Be sure your healthcare provider knows about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don’t need a prescription and any illegal drugs you may use.

Online Medical Reviewer:Chad Haldeman-Englert MD
Online Medical Reviewer:Raymond Turley Jr PA-C
Online Medical Reviewer:Tara Novick BSN MSN

Date Last Reviewed:9/1/2022

© 2000-2024 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

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Quantitative Influenza Antibody (Nasal or Throat Swab) (2024)

FAQs

Quantitative Influenza Antibody (Nasal or Throat Swab)? ›

This test is done with a sample of mucus or other fluid from your respiratory system. Your healthcare provider will wipe a sterile swab inside your nose or throat. Another method of doing this test is done with a nasopharyngeal aspirate (NPA).

What is the test for influenza A antibodies? ›

Proper serological testing for diagnosis of influenza requires paired acute and convalescent sera collected 2-3 weeks apart, with reliable testing at a limited number of public health or research laboratories to assess a 4-fold or greater rise in influenza virus strain-specific antibodies.

What is the swab test for the flu? ›

These tests include reverse transcription polymerase chain reaction (RT-PCR), viral culture, and immunofluorescence assays. All of these tests require that a health care provider swipe the inside of your nose or the back of your throat with a swab and then send the swab for testing.

What does it mean when the flu antigen is positive? ›

A positive test result means you may have the flu. It's possible to have a false positive, which means your test says you have the flu, but you really don't. Depending on your health, your provider may prescribe medicine to help prevent the flu from becoming a more serious illness.

How long can you test positive for influenza? ›

In very young children, influenza viruses can be shed for longer periods; therefore, in some instances, testing for a few days after this period may still detect influenza viruses. Immunosuppressed persons may have detectable influenza viruses in respiratory specimens for prolonged periods (weeks to months).

What is a quantitative influenza antibody test? ›

What is this test? This test checks for flu (influenza) antibodies in fluid from your nose or throat. The flu is a common illness of the respiratory system. It can have serious health effects.

What does positive antibody test mean? ›

A: A positive antibody test result could mean you previously had a SARS-CoV-2 infection or COVID-19. A positive antibody test could also mean the test is detecting antibodies in your blood in response to your COVID-19 vaccine. Not all SARS-CoV-2 antibody tests will detect antibodies in response to a COVID-19 vaccine.

Is flu test a nose or throat swab? ›

1 Tilt patient's head back 70 degrees. 2 Insert swab into nostril. (Swab should reach depth equal to distance from nostrils to outer opening of the ear.) Leave swab in place for several seconds to absorb secretions.

How accurate is the flu swab? ›

A rapid antigen flu test (rapid influenza diagnostic test, or RIDT) is the least accurate type of flu test. They have moderate sensitivity (50% to 70%) and high specificity. Sensitivity refers to a test's ability to determine that you have a disease or illness — you're positive for the illness.

What does it mean to be influenza B positive? ›

Influenza B is a common type of flu virus that causes symptoms like fever, headache, chills, cough, congestion, and body aches. This type of flu is highly contagious. While anyone can develop flu type B, young children and people with underlying health conditions have the highest risk.

How long is influenza contagious? ›

Period of Contagiousness

People with flu are most contagious during the first 3 days of their illness. Some otherwise healthy adults may be able to infect others beginning one day before symptoms develop and up to five to seven days after becoming sick.

Is flu A or B worse? ›

Type A influenza is generally considered worse than type B influenza. This is because the symptoms are often more severe in type A influenza than in type B influenza. Type A influenza is more common than type B influenza. Researchers suggest that most adults have considerable immunity against type B influenza.

Does a positive flu test mean contagious? ›

A positive result means that the RIDT detected influenza viral antigen, but does not necessarily mean viable influenza virus is present or that the patient is contagious.

How long do you have to quarantine with the flu? ›

Note: Not everyone with flu will have a fever. People with suspected or confirmed flu, who do not have a fever, should stay home from work at least 5 days after the onset of symptoms. People with flu are most contagious during the first 3 days of their illness.

Does influenza need quarantine? ›

Influenza: After close contact with someone who has flu, staying home is not required, unless symptoms occur. Home quarantine means avoiding other people. Home Isolation for Sick People with Symptoms. Home isolation for COVID-19 is required for at least 5 full days or longer.

Can you be around someone with the flu and not get it? ›

Even if you try your best to stay healthy when someone in the house has the flu, there's still a chance that you'll become infected. The flu causes symptoms that range from mild to severe, and if you live with certain medical conditions such as heart disease, getting the flu can increase your risk of complications.

Is there a test for influenza type A? ›

A PCR test can detect the genes of the virus or bacteria causing your symptoms. You can also buy over-the-counter rapid antigen tests (RAT) to diagnose the flu at home. Usually, these tests can tell you if you have: influenza A.

Do you have antibodies after influenza A? ›

Following influenza virus infection or receipt of a flu vaccine, the body's immune system develops antibodies that recognize and bind to “antigenic sites,” which are regions found on an influenza virus' surface proteins.

What are the levels of influenza antibodies? ›

Reference Range: Influenza A Virus Antibody, IgG: 0.89 IV or less: Negative - No significant level of influenza A virus IgG antibody detected. 0.90-1.10 IV: Equivocal - Questionable presence of influenza A virus IgG antibody detected. Repeat testing in 10-14 days may be helpful.

What is the test for virus antibodies? ›

Antibody testing shows whether you have antibodies to the virus that causes COVID-19, also called coronavirus disease 2019. Having antibodies suggests you've either had an infection with the virus in the past or you've had the COVID-19 vaccine. Antibody testing is not used to diagnose COVID-19.

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